Protein: DFM1
DER1-like family member protein 1

Gene: DFM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: Q12743

Gene Ontology (top 5):
GO:0005047 - signal recognition particle binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0036503 - ERAD pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

680198

CDC48
Cell division control protein 48

6

7

Small-scale

0.726

High

1085055

DFM1
DER1-like family member protein 1

1

14

Small-scale

0.665

High

798592

UBX7
UBX domain-containing protein 7

2

9

Small-scale

0.625

High

1043827

USA1
U1 SNP1-associating protein 1

2

1

Small-scale

0.625

High

797819

DER1
Degradation in the endoplasmic reticulum protein 1

1

1

Small-scale

0.618

High

1052332

HRD3
ERAD-associated E3 ubiquitin-protein ligase component HRD3

2

3

Small-scale

0.611

High

1061660

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

2

8

Small-scale

0.611

High

1046152

UBX2
UBX domain-containing protein 2

2

1

Small-scale

0.601

High

554457

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

2

0

Small-scale

0.559

High

754459

NPL4
Nuclear protein localization protein 4

1

2

Small-scale

0.536

High

1085056

OS9
Protein OS-9 homolog

1

1

Small-scale

0.536

High

916761

UFD1
Ubiquitin fusion degradation protein 1

1

1

Small-scale

0.515

High

757917

UBX1
UBX domain-containing protein 1

1

0

Small-scale

0.513

High

1030275

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

1

High-throughput

0.501

High

1042505

PEX29
Peroxisomal membrane protein PEX29

1

0

High-throughput

0.486

High

803731

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.479

High

822291

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

1

Small-scale

0.479

High

1085057

ENV10
SRP-independent targeting protein 2

1

2

High-throughput

0.479

High

726128

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

0

Small-scale

0.458

High

797096

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

481828

HSP73
Heat shock protein SSA3

1

5

High-throughput

0.445

High

525684

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

528130

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

546903

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

597317

BIP
Endoplasmic reticulum chaperone BiP

1

1

Small-scale

0.445

High

816491

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

435461

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

556584

STE6
Alpha-factor-transporting ATPase

1

2

Small-scale

0.437

High

624829

PMA2
Plasma membrane ATPase 2

1

4

High-throughput

0.437

High

708645

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

751146

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

3

Small-scale

0.437

High

758472

YKK0
Probable intramembrane protease YKL100C

1

2

Small-scale

0.437

High

815963

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

1

High-throughput

0.437

High

793023

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.417

High

742773

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.407

High

812940

UIP3
ULP1-interacting protein 3

1

0

High-throughput

0.265

Low

864870

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.265

Low

740637

IME2
Meiosis induction protein kinase IME2/SME1

1

0

High-throughput

0.261

Low

383021

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

455337

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

514908

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

741201

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.249

Low

802059

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.249

Low

850289

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

881477

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

1031774

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025