Protein: NKP2
Inner kinetochore subunit NKP2 (Constitutive centromere-associated network protein NKP2) (Non-essential kinetochore protein 2)

Gene: NKP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: Q06162

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031511 - Mis6-Sim4 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797908

CENPU
Inner kinetochore subunit AME1

5

0

Small-scale

0.866

High

1053961

NKP1
Inner kinetochore subunit NKP1

7

0

Small-scale

0.712

High

826849

DSN1
Kinetochore-associated protein DSN1

6

0

Small-scale

0.688

High

919464

CENPQ
Inner kinetochore subunit OKP1

4

0

High-throughput

0.661

High

1053955

CENPH
Inner kinetochore subunit MCM16

3

0

Small-scale

0.630

High

1038160

CENPP
Inner kinetochore subunit CTF19

3

0

High-throughput

0.625

High

779352

CENPA
Histone H3-like centromeric protein CSE4

3

0

Small-scale

0.606

High

807026

CENPN
Inner kinetochore subunit CHL4

2

0

Small-scale

0.576

High

850696

CENPT
Inner kinetochore subunit CNN1

2

0

Small-scale

0.559

High

744926

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.518

High

893161

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.494

High

893227

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.494

High

792959

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.493

High

797129

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.493

High

1053946

CENPO
Inner kinetochore subunit MCM21

1

0

High-throughput

0.493

High

755300

NUF2
Kinetochore protein NUF2

1

0

High-throughput

0.493

High

824872

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.493

High

917733

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.493

High

921106

PRS10
26S proteasome subunit RPT4

1

1

High-throughput

0.481

High

815576

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.480

High

864433

IKS1
Probable serine/threonine-protein kinase IKS1

1

0

High-throughput

0.480

High

454049

GCR1
Glycolytic genes transcriptional activator GCR1

1

0

High-throughput

0.460

High

664351

SSD1
Protein SSD1

1

0

High-throughput

0.460

High

678846

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.460

High

782595

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.460

High

794764

RTG3
Retrograde regulation protein 3

1

0

High-throughput

0.460

High

796372

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

823224

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

858475

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.460

High

863953

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.460

High

867876

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.460

High

898946

PHO23
Transcriptional regulatory protein PHO23

1

0

High-throughput

0.460

High

1033892

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.460

High

1044885

LIC4
Protein ATC1/LIC4

1

0

High-throughput

0.460

High

1053945

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.460

High

1053951

PALA
pH-response regulator protein palA/RIM20

1

0

High-throughput

0.460

High

1053959

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.460

High

1053960

AHC1
Protein AHC1

1

0

High-throughput

0.460

High

1053962

NOT5
General negative regulator of transcription subunit 5

1

0

High-throughput

0.460

High

793564

ADH5
Alcohol dehydrogenase 5

1

0

High-throughput

0.458

High

1053953

PSH1
RING finger protein PSH1

1

0

Small-scale

0.458

High

1053963

CENPI
Inner kinetochore subunit CTF3

1

0

Small-scale

0.458

High

742440

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

805703

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.438

High

525209

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

546349

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

1053952

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.426

High

836104

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.269

Low

1053571

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.265

Low

672462

STE50
Protein STE50

1

0

High-throughput

0.251

Low

735676

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

779804

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.251

Low

806446

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

817765

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

818344

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.251

Low

864584

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

918769

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

1040694

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.251

Low

1053640

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

1053947

IRC3
Putative ATP-dependent helicase IRC3

1

0

High-throughput

0.251

Low

1053948

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.251

Low

1053949

ATG20
Autophagy-related protein 20

1

0

High-throughput

0.251

Low

1053950

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

1053954

NYV1
Vacuolar v-SNARE NYV1

1

0

High-throughput

0.251

Low

1053956

BBP1
Spindle pole component BBP1

1

0

High-throughput

0.251

Low

1053957

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

1053958

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low

1053964

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.251

Low

399379

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

0

High-throughput

0.249

Low

533528

AK
Aspartokinase

1

0

High-throughput

0.249

Low

808586

GGC1
Mitochondrial GTP/GDP carrier protein 1

1

0

High-throughput

0.249

Low

917420

MTHR2
Methylenetetrahydrofolate reductase 2

1

0

High-throughput

0.249

Low

850653

ERJ5
ER-localized J domain-containing protein 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025