Protein: PNC1
Nicotinamidase (EC 3.5.1.19) (Nicotinamide deamidase) (NAMase)

Gene: PNC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P53184

Gene Ontology (top 5):
GO:0000183 - rDNA heterochromatin formation
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

918015

PNC1
Nicotinamidase

1

1

High-throughput

0.656

High

393069

HSP82
ATP-dependent molecular chaperone HSP82

3

1

High-throughput

0.633

High

918020

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

3

0

Small-scale

0.614

High

918022

IMA1
Importin subunit alpha

2

0

High-throughput

0.594

High

579777

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

752535

HSP78
Heat shock protein 78, mitochondrial

2

1

High-throughput

0.584

High

524631

HSP71
Heat shock protein SSA1

2

0

High-throughput

0.559

High

850112

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

645956

DBF2
Cell cycle protein kinase DBF2

1

1

High-throughput

0.536

High

836621

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

0

High-throughput

0.518

High

460994

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.513

High

684634

CDC20
APC/C activator protein CDC20

1

0

High-throughput

0.513

High

794281

CHK1
Serine/threonine-protein kinase CHK1

1

0

High-throughput

0.513

High

918017

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

798452

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.486

High

918023

MUK1
Protein MUK1

1

0

High-throughput

0.486

High

545652

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.479

High

727197

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

918018

CBK1
Serine/threonine-protein kinase CBK1

1

2

High-throughput

0.479

High

649231

SAN1
Protein SAN1

1

0

Small-scale

0.460

High

743406

TOR2
Serine/threonine-protein kinase TOR2

1

0

High-throughput

0.460

High

806320

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

453975

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.458

High

510665

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

558810

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

617949

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

0

High-throughput

0.458

High

646144

NPR1
Nitrogen permease reactivator protein

1

0

High-throughput

0.458

High

670945

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

707709

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

739418

ZUO1
Zuotin

1

0

Small-scale

0.458

High

746744

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.458

High

747957

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

754170

MSN2
Zinc finger protein MSN2

1

0

High-throughput

0.458

High

797314

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.458

High

803494

TDA3
Putative oxidoreductase TDA3

1

0

High-throughput

0.458

High

806775

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

817450

RGI1
Respiratory growth induced protein 1

1

0

High-throughput

0.458

High

818547

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

863160

FYV8
Protein FYV8

1

0

High-throughput

0.458

High

918016

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

918019

BOP3
Protein BOP3

1

0

High-throughput

0.458

High

918021

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.458

High

918025

VID22
Vacuolar import and degradation protein 22

1

0

High-throughput

0.458

High

918029

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

819331

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

918024

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.426

High

918030

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

812502

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

865925

BUD4
Bud site selection protein 4

1

0

High-throughput

0.249

Low

881394

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

918026

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low

918027

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

918028

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

634264

NUP1
Nucleoporin NUP1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025