Protein: MLC1
Myosin light chain 1 (Calmodulin-like myosin light chain MLC1) (Myosin-2 light chain)

Gene: MLC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 113
UniProt ID: P53141

Gene Ontology (top 5):
GO:0000142 - cellular bud neck contractile ring
GO:0000920 - septum digestion after cytokinesis
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0005934 - cellular bud tip

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585348

MYO2
Myosin-2

13

17

Small-scale

0.981

High

859593

IQG1
Ras GTPase-activating-like protein IQG1

8

20

Small-scale

0.970

High

446196

MYO1
Myosin-1

7

16

Small-scale

0.962

High

691272

MYO4
Myosin-4

4

17

High-throughput

0.896

High

420311

CALM
Calmodulin

3

13

High-throughput

0.867

High

859560

MLC1
Myosin light chain 1

2

13

Small-scale

0.775

High

859574

STE20
Serine/threonine-protein kinase STE20

2

1

Small-scale

0.754

High

701907

SWE1
Mitosis inhibitor protein kinase SWE1

1

3

High-throughput

0.691

High

747621

SHE3
SWI5-dependent HO expression protein 3

5

0

High-throughput

0.688

High

859567

MPS1
Serine/threonine-protein kinase MPS1

1

3

High-throughput

0.618

High

629291

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

7

High-throughput

0.595

High

783849

BUB1
Checkpoint serine/threonine-protein kinase BUB1

1

13

High-throughput

0.595

High

627651

NAP1
Nucleosome assembly protein

2

1

High-throughput

0.576

High

859569

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

1

High-throughput

0.567

High

761435

PIK1
Phosphatidylinositol 4-kinase PIK1

1

4

Small-scale

0.555

High

859573

TOM1
E3 ubiquitin-protein ligase TOM1

2

9

High-throughput

0.549

High

859594

HSP42
Heat shock protein 42

2

1

High-throughput

0.537

High

859578

CYK2
Cytokinesis protein 2

1

1

Small-scale

0.516

High

761185

RGA1
Rho-type GTPase-activating protein 1

1

13

High-throughput

0.515

High

764098

RV167
Reduced viability upon starvation protein 167

1

6

High-throughput

0.515

High

859561

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.515

High

859582

MLC2
Myosin light chain 2

1

19

High-throughput

0.515

High

859592

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.515

High

690630

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

3

High-throughput

0.514

High

715263

TREB
Probable trehalase

1

0

High-throughput

0.493

High

783879

BUD6
Bud site selection protein 6

1

0

High-throughput

0.493

High

859583

BSP1
Protein BSP1

1

0

High-throughput

0.493

High

667874

MCM5
Minichromosome maintenance protein 5

1

1

High-throughput

0.489

High

784626

BNI1
Protein BNI1

1

4

Small-scale

0.481

High

429232

SEC4
Ras-related protein SEC4

1

2

Small-scale

0.479

High

544115

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

859568

NUM1
Nuclear migration protein NUM1

1

17

High-throughput

0.479

High

424890

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.470

High

584180

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.470

High

593671

DBP4
ATP-dependent RNA helicase HCA4

1

3

High-throughput

0.470

High

687566

PYC2
Pyruvate carboxylase 2

1

1

High-throughput

0.470

High

697102

RAD23
UV excision repair protein RAD23

1

1

High-throughput

0.470

High

746817

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.470

High

747015

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

14

High-throughput

0.470

High

837405

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

High-throughput

0.470

High

859579

CORO
Coronin-like protein

1

3

High-throughput

0.470

High

768293

PEA2
Protein PEA2

1

0

Small-scale

0.460

High

491896

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

494504

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

512076

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

540610

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.445

High

768986

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

812295

BUD4
Bud site selection protein 4

1

0

Small-scale

0.438

High

407196

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

413617

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

471160

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

638815

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

645551

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

662828

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

663895

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

730023

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.437

High

752564

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

820070

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

859563

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.437

High

859585

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

859588

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

859589

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.437

High

859590

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

859595

LAS17
Proline-rich protein LAS17

1

6

Small-scale

0.437

High

633408

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.407

High

695142

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.407

High

696020

HSP79
Heat shock protein homolog SSE2

1

6

High-throughput

0.407

High

731126

LHS1
Heat shock protein 70 homolog LHS1

1

5

High-throughput

0.407

High

766121

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.407

High

859584

BRE1
E3 ubiquitin-protein ligase BRE1

1

16

High-throughput

0.407

High

859562

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

345243

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.269

Low

579859

DDR48
Stress protein DDR48

1

0

High-throughput

0.269

Low

687836

MSS51
Protein MSS51, mitochondrial

1

0

High-throughput

0.269

Low

688104

SSH4
Protein SSH4

1

0

High-throughput

0.269

Low

691568

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.269

Low

731924

ELF1
Transcription elongation factor 1

1

0

High-throughput

0.269

Low

745779

NU170
Nucleoporin NUP170

1

0

High-throughput

0.269

Low

746639

RKM3
Ribosomal lysine N-methyltransferase 3

1

0

High-throughput

0.269

Low

764007

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.269

Low

819520

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.269

Low

820009

RAD17
DNA damage checkpoint control protein RAD17

1

0

High-throughput

0.269

Low

847141

SHE4
SWI5-dependent HO expression protein 4

1

0

High-throughput

0.269

Low

859566

FAP1
FKBP12-associated protein 1

1

0

High-throughput

0.269

Low

859571

TOF2
Topoisomerase 1-associated factor 2

1

0

High-throughput

0.269

Low

859572

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.269

Low

859575

SRC1
Inner nuclear membrane protein SRC1

1

0

High-throughput

0.269

Low

859576

RAD33
DNA repair protein RAD33

1

0

High-throughput

0.269

Low

859577

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.269

Low

859580

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.269

Low

859587

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.269

Low

859591

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.269

Low

859596

KCS1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.269

Low

859597

YO098
Uncharacterized protein YOL098C

1

0

High-throughput

0.269

Low

375451

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

408020

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

426055

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

480783

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

519612

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

Small-scale

0.249

Low

634695

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

701512

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

706384

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

716471

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

748162

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

762398

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

817361

HGH1
Protein HGH1

1

0

Small-scale

0.249

Low

859565

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

859570

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

859581

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

859586

AB140
tRNA(Thr)

1

0

High-throughput

0.249

Low

859564

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.238

Low

757097

SET5
Histone-lysine N-methyltransferase SET5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024