Protein: SP381
Pre-mRNA-splicing factor SPP381 (Suppressor of PRP38-1 mutation)

Gene: SP381, SPP381
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P38282

Gene Ontology (top 5):
GO:0000349 - generation of catalytic spliceosome for first transesterification step
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797316

PRP38
Pre-mRNA-splicing factor 38

7

0

Small-scale

0.717

High

797328

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

5

0

Small-scale

0.686

High

797306

RSMB
Small nuclear ribonucleoprotein-associated protein B

5

0

High-throughput

0.684

High

744107

BRR2
Pre-mRNA-splicing helicase BRR2

5

0

Small-scale

0.682

High

797329

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

0

Small-scale

0.661

High

625005

PRP6
Pre-mRNA-splicing factor 6

3

0

High-throughput

0.634

High

627848

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

3

0

High-throughput

0.634

High

780175

SN114
Pre-mRNA-splicing factor SNU114

3

0

High-throughput

0.634

High

797312

PRP31
Pre-mRNA-processing factor 31

3

0

High-throughput

0.634

High

797319

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

3

0

High-throughput

0.634

High

797327

RU2A
U2 small nuclear ribonucleoprotein A'

3

0

High-throughput

0.634

High

625093

PRP9
Pre-mRNA-splicing factor PRP9

2

0

High-throughput

0.595

High

739242

PRP21
Pre-mRNA-splicing factor PRP21

2

0

High-throughput

0.595

High

797308

MSL1
U2 small nuclear ribonucleoprotein B''

2

0

High-throughput

0.595

High

797313

SF3B1
U2 snRNP component HSH155

2

0

High-throughput

0.595

High

797318

CUS1
Cold sensitive U2 snRNA suppressor 1

2

0

High-throughput

0.595

High

797321

RSE1
Pre-mRNA-splicing factor RSE1

2

0

High-throughput

0.595

High

797325

PRP11
Pre-mRNA-splicing factor PRP11

2

0

High-throughput

0.595

High

751731

PRP8
Pre-mRNA-splicing factor 8

2

0

High-throughput

0.585

High

523759

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.552

High

526535

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

544659

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

721891

XPO1
Exportin-1

1

0

High-throughput

0.513

High

792780

ANM1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.480

High

797311

LSM8
LSM2-LSM8 complex subunit LSM8

1

1

High-throughput

0.479

High

749666

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

797309

GZF3
Protein GZF3

1

0

High-throughput

0.460

High

797323

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

706935

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

781552

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

797307

RUXG
Small nuclear ribonucleoprotein G

1

0

High-throughput

0.458

High

797310

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.458

High

797314

PNC1
Nicotinamidase

1

0

High-throughput

0.458

High

797315

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.458

High

797317

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

797322

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

797324

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.458

High

797326

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

741464

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

382059

H4
Histone H4

1

0

High-throughput

0.426

High

670628

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

739134

PRP19
Pre-mRNA-processing factor 19

1

0

Small-scale

0.426

High

758085

CASP
Protein CASP

1

0

High-throughput

0.251

Low

558691

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

746725

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.249

Low

797320

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025