Protein: HOLD
DNA polymerase III subunit psi (EC 2.7.7.7) (Accessory clamp loader complex subunit psi) (Replication clamp loader subunit HolD)

Gene: HOLD
Organism: Escherichia coli K-12
Interactions: 25
UniProt ID: P28632

Gene Ontology (top 5):
GO:0003887 - DNA-directed DNA polymerase activity
GO:0006260 - DNA replication
GO:0006261 - DNA-templated DNA replication
GO:0008408 - 3'-5' exonuclease activity
GO:0009314 - response to radiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704179

HOLC
DNA polymerase III subunit chi

10

0

Small-scale

0.929

High

445424

DPO3X
DNA polymerase III subunit tau

9

0

Small-scale

0.918

High

704171

HOLB
DNA polymerase III subunit delta'

4

1

Small-scale

0.696

High

571327

TOP3
DNA topoisomerase 3

3

0

High-throughput

0.641

High

704148

HOLA
DNA polymerase III subunit delta

3

0

Small-scale

0.634

High

578357

RECQ
ATP-dependent DNA helicase RecQ

2

0

High-throughput

0.585

High

501535

SSB
Single-stranded DNA-binding protein

2

0

High-throughput

0.559

High

395125

DPO3E
DNA polymerase III subunit epsilon

1

0

High-throughput

0.537

High

522207

DPO3A
DNA polymerase III subunit alpha

1

0

High-throughput

0.537

High

498564

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.464

High

704178

HOLD
DNA polymerase III subunit psi

1

0

Small-scale

0.438

High

704181

YNBC
Uncharacterized protein YnbC

2

0

High-throughput

0.330

High

521480

SECA
Protein translocase subunit SecA

2

0

High-throughput

0.318

High

492533

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.313

High

501242

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.313

High

492261

PYRI
Aspartate carbamoyltransferase regulatory chain

1

0

High-throughput

0.279

Low

496615

MUG
G/U mismatch-specific DNA glycosylase

1

0

High-throughput

0.279

Low

498122

YCGL
Protein YcgL

1

0

High-throughput

0.279

Low

704180

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.279

Low

492961

RL28
Large ribosomal subunit protein bL28

1

0

High-throughput

0.253

Low

495843

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.253

Low

497516

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.253

Low

495096

TRMD
tRNA

1

0

High-throughput

0.249

Low

501438

UGPB
sn-glycerol-3-phosphate-binding periplasmic protein UgpB

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025