Protein: PPBT
Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNS-ALP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1)

Gene: PPBT, ALPL
Organism: Homo sapiens
Interactions: 31
UniProt ID: P05186

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001649 - osteoblast differentiation
GO:0001958 - endochondral ossification
GO:0003006 - developmental process involved in reproduction
GO:0004035 - alkaline phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

426031

VMP1
Vacuole membrane protein 1

1

2

High-throughput

0.536

High

426018

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.529

High

426011

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

1

0

Small-scale

0.480

High

426010

RHOC
Rho-related GTP-binding protein RhoC

1

5

High-throughput

0.479

High

426012

RAC2
Ras-related C3 botulinum toxin substrate 2

1

4

High-throughput

0.479

High

426015

CDC42
Cell division control protein 42 homolog

1

4

High-throughput

0.479

High

426016

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.479

High

426017

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.479

High

426023

IF4A2
Eukaryotic initiation factor 4A-II

1

2

High-throughput

0.479

High

426025

RHOH
Rho-related GTP-binding protein RhoH

1

6

High-throughput

0.479

High

426028

ABCF1
ATP-binding cassette sub-family F member 1

1

1

High-throughput

0.479

High

426029

RND1
Rho-related GTP-binding protein Rho6

1

6

High-throughput

0.479

High

426030

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

426020

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

426027

CD177
CD177 antigen

1

2

Small-scale

0.445

High

426021

TRAF2
TNF receptor-associated factor 2

1

2

Small-scale

0.437

High

426022

TRAF3
TNF receptor-associated factor 3

1

2

Small-scale

0.437

High

426034

CECR2
Chromatin remodeling regulator CECR2

1

1

High-throughput

0.437

High

426037

FBX6
F-box only protein 6

1

1

High-throughput

0.437

High

426038

HDAC6
Protein deacetylase HDAC6

1

3

High-throughput

0.437

High

426039

BAZ1B
Tyrosine-protein kinase BAZ1B

1

1

High-throughput

0.437

High

426014

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

1

Small-scale

0.417

High

426024

SPCS2
Signal peptidase complex subunit 2

2

0

High-throughput

0.328

High

426035

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.328

High

426032

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

426040

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

426019

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.261

Low

426033

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

0

Small-scale

0.249

Low

426036

SIK2
Serine/threonine-protein kinase SIK2

1

0

Small-scale

0.249

Low

426013

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

426026

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025