Protein: DB121
Beta-defensin 121 (Beta-defensin 21) (DEFB-21) (Defensin, beta 121)

Gene: DB121, DEFB121
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q5J5C9

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0045087 - innate immune response
GO:0050829 - defense response to Gram-negative bacterium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

551863

CO6A2

2

0

High-throughput

0.602

High

1205422

VWDE
von Willebrand factor D and EGF domain-containing protein

2

0

High-throughput

0.602

High

1087054

FSTL1
Follistatin-related protein 1

1

0

High-throughput

0.513

High

1205416

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.513

High

725612

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

2

0

High-throughput

0.328

High

1105469

OS9
Protein OS-9

2

0

High-throughput

0.328

High

1204859

MKS3
Meckelin

2

0

High-throughput

0.328

High

1205424

DYT2B
Dynein light chain Tctex-type protein 2B

2

0

High-throughput

0.328

High

683252

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.316

High

870725

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.316

High

1205417

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1205419

I27RA
Interleukin-27 receptor subunit alpha

2

0

High-throughput

0.316

High

1205420

LAYN
Layilin

2

0

High-throughput

0.316

High

1205423

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.316

High

1205425

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

1205426

NECT4
Nectin-4

2

0

High-throughput

0.316

High

1205428

CLC2D
C-type lectin domain family 2 member D

2

0

High-throughput

0.316

High

1205421

SYNE4
Nesprin-4

1

0

High-throughput

0.299

High

1205427

SE1L1
Protein sel-1 homolog 1

1

0

High-throughput

0.279

Low

1205418

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025