HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: Q6AXH7 (Q6AXH7)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356)
Gene: Ezh2

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	23624931
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~preSET_CXC, Histone~SET
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 742
+	Mm
		1017354 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		EZH2_MOUSE (1-742): 0: 778: 98.00
+	Hs
		998359 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		EZH2_HUMAN (1-742): 0: 773: 96.41
+	At
		947409 H33_ARATH (1-136): 3.85e-60: 183: 95.59		SUVH4_ARATH (171-729): 3.47e-109: 346: 12.74
+	Hs
		998772 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SETD2_HUMAN (118-728): 8.25e-80: 281: 15.48
+	Hs
		998846 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		ASH1L_HUMAN (325-729): 7.95e-76: 269: 20.00
+	Hs
		998234 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KMT2A_HUMAN (329-729): 9.62e-72: 258: 19.29
+	Hs
		998821 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		EHMT1_HUMAN (424-728): 1.19e-71: 256: 22.36
+	Mm
		1017384 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		EHMT2_MOUSE (430-728): 4.03e-71: 254: 24.45
+	Hs
		998691 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		EHMT2_HUMAN (430-728): 4.96e-70: 251: 24.14
+	Hs
		998807 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SUV92_HUMAN (424-730): 1.95e-74: 248: 23.78
+	Hs
		216410 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SUV91_HUMAN (421-727): 2.67e-73: 245: 22.60
+	Hs
		216415 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		SUV91_HUMAN (421-727): 2.67e-73: 245: 22.60
+	Hs
		355489 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		NSD2_HUMAN (551-723): 3.09e-55: 207: 30.56
+	Hs
		355497 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		NSD2_HUMAN (551-723): 3.09e-55: 207: 30.56
+	Hs
		998773 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		NSD3_HUMAN (551-723): 1.94e-54: 205: 30.56
+	Hs
		998694 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		NSD1_HUMAN (550-725): 8.91e-54: 203: 29.51
+	Hs
		998948 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SET1B_HUMAN (615-728): 1.14e-18: 93.6: 40.52
+	Mm
		1017365 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		SET1B_MOUSE (615-728): 8.16e-19: 94: 40.52
+	Hs
		175872 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SET1A_HUMAN (607-728): 2.38e-18: 92.4: 38.71
+	Mm
		97779 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		SET1A_MOUSE (607-728): 1.96e-18: 92.8: 38.71