HitPredict

Interactor 1: PP4C (A6H772)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16)
Gene: PPP4C

Interactor 2: F1MRS1 (F1MRS1)
Serine/threonine-protein phosphatase 4 regulatory subunit 1
Gene: PPP4R1

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	10026142
Identification Methods	chromatography technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HEAT~Metallophos
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 307 Bt			1 945
+	Hs
		952005 PP4C_HUMAN (1-307): 0: 537: 100.00		PP4R1_HUMAN (27-945): 0: 927: 83.53
+	Hs
		977548 PP2AB_HUMAN (6-307): 0: 525: 65.23		PP4R1_HUMAN (27-945): 0: 927: 83.53
+	Hs
		994309 PP2AA_HUMAN (6-307): 0: 524: 65.89		PP4R1_HUMAN (27-945): 0: 927: 83.53
+	Hs
		717747 PP4C_HUMAN (1-307): 0: 537: 100.00		2AAA_HUMAN (233-803): 3e-32: 135: 13.49
+	Hs
		718094 PP4C_HUMAN (1-307): 0: 537: 100.00		2AAB_HUMAN (233-804): 4.28e-31: 131: 14.26
+	Hs
		91606 PP2AB_HUMAN (6-307): 0: 525: 65.23		C9J9C1_HUMAN (236-803): 1.63e-32: 136: 13.56
+	Hs
		717759 PP2AB_HUMAN (6-307): 0: 525: 65.23		2AAA_HUMAN (233-803): 3e-32: 135: 13.49
+	Hs
		91607 PP2AA_HUMAN (6-307): 0: 524: 65.89		C9J9C1_HUMAN (236-803): 1.63e-32: 136: 13.56
+	Mm
		977639 PP2AB_MOUSE (6-307): 0: 525: 65.23		2AAA_MOUSE (233-803): 3.25e-32: 135: 13.49
+	Hs
		717766 PP2AA_HUMAN (6-307): 0: 524: 65.89		2AAA_HUMAN (233-803): 3e-32: 135: 13.49
+	Mm
		994011 PP2AA_MOUSE (6-307): 0: 524: 65.89		2AAA_MOUSE (233-803): 3.25e-32: 135: 13.49
+	Hs
		718098 PP2AB_HUMAN (6-307): 0: 525: 65.23		2AAB_HUMAN (233-804): 4.28e-31: 131: 14.26
+	Hs
		718101 PP2AA_HUMAN (6-307): 0: 524: 65.89		2AAB_HUMAN (233-804): 4.28e-31: 131: 14.26
+	Dm
		661918 PP2A_DROME (2-307): 0: 524: 64.05		2AAA_DROME (233-779): 8.37e-21: 99.6: 12.57
+	Hs
		951994 PP4C_HUMAN (1-307): 0: 537: 100.00		PP4R4_HUMAN (51-365): 1.15e-09: 64.5: 18.10
+	Sp
		661366 PP2A2_SCHPO (2-307): 0: 510: 63.40		2AAA_SCHPO (616-921): 4.06e-18: 91.1: 16.51
+	Mm
		1021492 PP4C_MOUSE (1-307): 0: 537: 100.00		PP4R4_MOUSE (51-365): 3.19e-09: 63: 17.29
+	Sp
		661356 PP2A1_SCHPO (2-307): 3.58e-154: 435: 63.19		2AAA_SCHPO (616-921): 4.06e-18: 91.1: 16.51
+	Sc
		660776 PP2A1_YEAST (4-307): 1.51e-148: 423: 60.98		2AAA_YEAST (19-366): 2.81e-15: 82.2: 14.89
+	Hs
		143674 PPP6_HUMAN (6-307): 1.54e-148: 420: 61.92		GCN1_HUMAN (13-925): 3.12e-13: 76.5: 12.56