HitPredict

Interactor 1: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Interactor 2: PP4R1 (Q8TF05)
Serine/threonine-protein phosphatase 4 regulatory subunit 1
Gene: PPP4R1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.80	0.833

Property	Details
Experiments	26186194, 26496610, 27880917, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HEAT~Metallophos
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Hs			1 950
+	Hs
		994309 PP2AA_HUMAN (1-309): 0: 533: 97.41		PP4R1_HUMAN (1-950): 0: 1060: 100.00
+	Hs
		952005 PP4C_HUMAN (4-309): 0: 512: 64.50		PP4R1_HUMAN (1-950): 0: 1060: 100.00
+	Bt
		64311 PP4C_BOVIN (4-309): 0: 512: 64.50		F1MRS1_BOVIN (18-950): 0: 1025: 83.87
+	Sp
		661366 PP2A2_SCHPO (5-309): 0: 508: 79.02		2AAA_SCHPO (4-385): 1.52e-29: 126: 13.37
+	Sp
		661356 PP2A1_SCHPO (7-309): 0: 504: 79.21		2AAA_SCHPO (4-385): 1.52e-29: 126: 13.37
+	Sc
		660839 PP2A2_YEAST (9-309): 0: 531: 76.08		2AAA_YEAST (190-836): 1.36e-15: 83.4: 15.05
+	Sc
		660776 PP2A1_YEAST (7-309): 0: 518: 74.92		2AAA_YEAST (190-836): 1.36e-15: 83.4: 15.05
+	Hs
		717759 PP2AB_HUMAN (1-309): 0: 533: 100.00		2AAA_HUMAN (674-930): 1.15e-10: 67.2: 17.97
+	Hs
		717766 PP2AA_HUMAN (1-309): 0: 533: 97.41		2AAA_HUMAN (674-930): 1.15e-10: 67.2: 17.97
+	Hs
		91606 PP2AB_HUMAN (1-309): 0: 533: 100.00		C9J9C1_HUMAN (686-930): 1.42e-10: 67.2: 18.38
+	Hs
		91607 PP2AA_HUMAN (1-309): 0: 533: 97.41		C9J9C1_HUMAN (686-930): 1.42e-10: 67.2: 18.38
+	Mm
		977639 PP2AB_MOUSE (1-309): 0: 533: 100.00		2AAA_MOUSE (674-930): 1.17e-10: 67.2: 17.97
+	Mm
		994011 PP2AA_MOUSE (1-309): 0: 532: 97.41		2AAA_MOUSE (674-930): 1.17e-10: 67.2: 17.97
+	Hs
		718098 PP2AB_HUMAN (1-309): 0: 533: 100.00		2AAB_HUMAN (67-715): 6.03e-10: 64.9: 13.40
+	Hs
		718101 PP2AA_HUMAN (1-309): 0: 533: 97.41		2AAB_HUMAN (67-715): 6.03e-10: 64.9: 13.40
+	Dm
		661918 PP2A_DROME (1-309): 0: 528: 94.50		2AAA_DROME (34-302): 8.12e-09: 61.4: 17.55
+	Hs
		951994 PP4C_HUMAN (4-309): 0: 512: 64.50		PP4R4_HUMAN (5-354): 8.58e-11: 68: 18.90
+	Mm
		1021492 PP4C_MOUSE (4-309): 0: 512: 64.50		PP4R4_MOUSE (5-354): 1.18e-10: 67.6: 17.63
+	Hs
		717747 PP4C_HUMAN (4-309): 0: 512: 64.50		2AAA_HUMAN (674-930): 1.15e-10: 67.2: 17.97
+	Hs
		718094 PP4C_HUMAN (4-309): 0: 512: 64.50		2AAB_HUMAN (67-715): 6.03e-10: 64.9: 13.40