HitPredict

Interactor 1: AT2C1 (P98194)
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) (SPCA1)
Gene: ATP2C1

Interactor 2: LPAR1 (Q92633)
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)
Gene: LPAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 919 Hs			1 364
+	Hs
		1023395 AT2C1_HUMAN (1-919): 0: 866: 100.00		LPAR2_HUMAN (23-364): 1.67e-72: 230: 53.06
+	Hs
		351888 AT2C1_HUMAN (1-919): 0: 866: 100.00		S1PR4_HUMAN (1-360): 5.92e-72: 230: 30.89
+	Hs
		1023384 AT2C1_HUMAN (1-919): 0: 866: 100.00		S1PR3_HUMAN (27-334): 9.64e-68: 219: 37.18
+	Hs
		711549 AT2C1_HUMAN (1-919): 0: 866: 100.00		NK3R_HUMAN (10-364): 6.78e-65: 214: 15.41
+	Hs
		638181 AT2C1_HUMAN (1-919): 0: 866: 100.00		S1PR1_HUMAN (10-333): 6.49e-62: 204: 36.86
+	Hs
		351870 AT1A3_HUMAN (10-905): 0: 803: 25.86		S1PR4_HUMAN (1-360): 5.92e-72: 230: 30.89
+	Hs
		420304 AT1A1_HUMAN (16-905): 0: 806: 26.22		ADRB2_HUMAN (54-357): 3.42e-68: 221: 17.02
+	Hs
		565577 AT1A3_HUMAN (10-905): 0: 803: 25.86		GPR12_HUMAN (58-329): 2.34e-68: 219: 29.09
+	Hs
		565565 AT1A3_HUMAN (10-905): 0: 803: 25.86		NK3R_HUMAN (10-364): 6.78e-65: 214: 15.41
+	Hs
		1372395 AT2A3_HUMAN (24-903): 0: 781: 31.72		LPAR2_HUMAN (23-364): 1.67e-72: 230: 53.06
+	Hs
		351938 AT2A3_HUMAN (24-903): 0: 781: 31.72		S1PR4_HUMAN (1-360): 5.92e-72: 230: 30.89
+	Hs
		174023 AT2A1_HUMAN (24-911): 0: 779: 31.07		LPAR1_HUMAN (1-364): 1.6e-72: 231: 100.00
+	Hs
		565554 AT1A3_HUMAN (10-905): 0: 803: 25.86		S1PR1_HUMAN (10-333): 6.49e-62: 204: 36.86
+	Hs
		565701 AT1A3_HUMAN (10-905): 0: 803: 25.86		NPFF1_HUMAN (11-363): 2.08e-61: 204: 19.47
+	Hs
		351873 AT2B4_HUMAN (8-913): 0: 756: 23.16		S1PR4_HUMAN (1-360): 5.92e-72: 230: 30.89
+	Hs
		598015 AT2A2_HUMAN (24-915): 0: 759: 32.01		CNR2_HUMAN (46-349): 4.81e-71: 227: 24.52
+	Hs
		638224 AT2A3_HUMAN (24-903): 0: 781: 31.72		S1PR1_HUMAN (10-333): 6.49e-62: 204: 36.86
+	Hs
		458268 AT2A2_HUMAN (24-915): 0: 759: 32.01		ADRB2_HUMAN (54-357): 3.42e-68: 221: 17.02
+	Hs
		221446 AT2B4_HUMAN (8-913): 0: 756: 23.16		OX2R_HUMAN (10-357): 3.22e-66: 217: 16.79
+	Hs
		598025 AT2A2_HUMAN (24-915): 0: 759: 32.01		OPRD_HUMAN (1-359): 4.51e-63: 207: 17.52