Interactor 1: INS (P01308)
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Gene: INS
Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 0.90 | 0.809 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Insulin~fn3, Furin-like~Insulin, Insulin~Recep_L_domain |
| Common GO terms | GO:0005159 - insulin-like growth factor receptor binding GO:0006355 - regulation of DNA-templated transcription GO:0007186 - G protein-coupled receptor signaling pathway GO:0008284 - positive regulation of cell population proliferation GO:0008286 - insulin receptor signaling pathway and 11 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
