HitPredict

Interactor 1: AT2C1 (P98194)
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) (SPCA1)
Gene: ATP2C1

Interactor 2: S1PR3 (Q99500)
Sphingosine 1-phosphate receptor 3 (S1P receptor 3) (S1P3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor Edg-3) (S1P receptor Edg-3)
Gene: S1PR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 919 Hs			1 378
+	Hs
		351888 AT2C1_HUMAN (1-919): 0: 866: 100.00		S1PR4_HUMAN (15-352): 1.92e-81: 255: 41.06
+	Hs
		1023395 AT2C1_HUMAN (1-919): 0: 866: 100.00		LPAR2_HUMAN (15-325): 7.4e-79: 247: 34.18
+	Hs
		1023376 AT2C1_HUMAN (1-919): 0: 866: 100.00		LPAR1_HUMAN (15-334): 1.2e-64: 211: 35.69
+	Hs
		711549 AT2C1_HUMAN (1-919): 0: 866: 100.00		NK3R_HUMAN (1-318): 2.23e-62: 208: 19.03
+	Hs
		638181 AT2C1_HUMAN (1-919): 0: 866: 100.00		S1PR1_HUMAN (4-369): 3.71e-61: 203: 49.60
+	Hs
		351870 AT1A3_HUMAN (10-905): 0: 803: 25.86		S1PR4_HUMAN (15-352): 1.92e-81: 255: 41.06
+	Hs
		351938 AT2A3_HUMAN (24-903): 0: 781: 31.72		S1PR4_HUMAN (15-352): 1.92e-81: 255: 41.06
+	Hs
		1372395 AT2A3_HUMAN (24-903): 0: 781: 31.72		LPAR2_HUMAN (15-325): 7.4e-79: 247: 34.18
+	Hs
		420304 AT1A1_HUMAN (16-905): 0: 806: 26.22		ADRB2_HUMAN (44-378): 2.74e-67: 220: 18.33
+	Hs
		565577 AT1A3_HUMAN (10-905): 0: 803: 25.86		GPR12_HUMAN (42-327): 1.29e-65: 213: 26.62
+	Hs
		565570 AT1A3_HUMAN (10-905): 0: 803: 25.86		OPRX_HUMAN (31-349): 4.4e-64: 210: 15.24
+	Hs
		565565 AT1A3_HUMAN (10-905): 0: 803: 25.86		NK3R_HUMAN (1-318): 2.23e-62: 208: 19.03
+	Hs
		565554 AT1A3_HUMAN (10-905): 0: 803: 25.86		S1PR1_HUMAN (4-369): 3.71e-61: 203: 49.60
+	Hs
		174023 AT2A1_HUMAN (24-911): 0: 779: 31.07		LPAR1_HUMAN (15-334): 1.2e-64: 211: 35.69
+	Hs
		638224 AT2A3_HUMAN (24-903): 0: 781: 31.72		S1PR1_HUMAN (4-369): 3.71e-61: 203: 49.60
+	Hs
		458268 AT2A2_HUMAN (24-915): 0: 759: 32.01		ADRB2_HUMAN (44-378): 2.74e-67: 220: 18.33
+	Hs
		598015 AT2A2_HUMAN (24-915): 0: 759: 32.01		CNR2_HUMAN (40-341): 3.84e-68: 220: 24.84
+	Hs
		598025 AT2A2_HUMAN (24-915): 0: 759: 32.01		OPRD_HUMAN (9-345): 1.03e-67: 219: 17.29
+	Hs
		221446 AT2B4_HUMAN (8-913): 0: 756: 23.16		OX2R_HUMAN (9-365): 3.81e-64: 212: 15.11
+	Hs
		477152 AT2A2_HUMAN (24-915): 0: 759: 32.01		ACM5_HUMAN (31-236): 1.74e-11: 67.4: 27.78