HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: TSSK6 (Q9BXA6)
Testis-specific serine/threonine-protein kinase 6 (TSK-6) (TSSK-6) (Testis-specific kinase 6) (EC 2.7.11.1) (Cancer/testis antigen 72) (CT72) (Serine/threonine-protein kinase SSTK) (Small serine/threonine kinase)
Gene: TSSK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	25852190, 33961781, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 273
+	Hs
		1034968 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		MARK4_HUMAN (4-273): 6.16e-122: 366: 36.90
+	Hs
		625378 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		CDK2_HUMAN (9-272): 6.13e-123: 354: 24.83
+	Hs
		1034972 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		TSSK2_HUMAN (1-268): 1.39e-79: 246: 46.35
+	Hs
		1034988 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		TSSK1_HUMAN (1-273): 2.18e-79: 245: 46.24
+	Hs
		972568 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		TSSK2_HUMAN (1-268): 1.39e-79: 246: 46.35
+	Hs
		972577 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		TSSK1_HUMAN (1-273): 2.18e-79: 245: 46.24
+	Hs
		118784 AIP_HUMAN (144-414): 1.52e-49: 173: 16.72		TSSK6_HUMAN (1-273): 2.14e-148: 417: 100.00
+	Hs
		1035062 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		SIK3_HUMAN (12-272): 1.41e-45: 165: 37.02
+	Hs
		118785 AIP_HUMAN (144-414): 1.52e-49: 173: 16.72		TSSK1_HUMAN (1-273): 2.18e-79: 245: 46.24
+	Hs
		684963 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		TSSK2_HUMAN (1-268): 1.39e-79: 246: 46.35
+	Hs
		684999 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		TSSK1_HUMAN (1-273): 2.18e-79: 245: 46.24
+	Hs
		685124 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		SIK3_HUMAN (12-272): 1.41e-45: 165: 37.02