HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ELOC (Q15369)
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)
Gene: ELOC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.864

The method score is based on:

Property Details
Experiments 35563538, 21145461, 21988832
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Skp1_POZ
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 768
Hs

1 112
+ Hs
+ Hs
+ Dm
+ Ce
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024