HitPredict

Interactor 1: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 15082779, 16628223, 25742295, 17467235, 12473661, 10428811, 28514442, 32203420, 33961781, 35271311, 40437099, unassigned2213, 21295525, 16787945
Identification Methods affinity chromatography technology, pull down, two hybrid, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArfGap~PH, GIT_SHD~RhoGEF67_u2
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0030027 - lamellipodium
GO:0043005 - neuron projection
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 803
Hs

1 761
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Gg
+ Hs
+ Rn
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025