HitPredict

Interactor 1: G5EGG2 (G5EGG2)
Homolog of S. Pombe Rad (Rad17-like protein)
Gene: hpr-17

Interactor 2: RFC4 (P53016)
Replication factor C subunit 4 (Activator 1 subunit 4)
Gene: rfc-4

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	12679813, 11778048, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	AAA~Rad17
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006281 - DNA repair
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 514 Ce			1 334
+	Hs
		769667 RFC1_HUMAN (2-512): 7.05e-88: 294: 13.29		RFC4_HUMAN (8-333): 1.06e-89: 274: 41.03
+	Hs
		769933 RFC1_HUMAN (2-512): 7.05e-88: 294: 13.29		RFC5_HUMAN (1-332): 1.3e-80: 250: 33.53
+	Hs
		298577 RAD17_HUMAN (4-508): 4.4e-81: 267: 21.96		RFC4_HUMAN (8-333): 1.06e-89: 274: 41.03
+	Hs
		769815 RFC1_HUMAN (2-512): 7.05e-88: 294: 13.29		RFC2_HUMAN (13-332): 8.84e-79: 246: 29.38
+	Hs
		298580 RAD17_HUMAN (4-508): 4.4e-81: 267: 21.96		RFC5_HUMAN (1-332): 1.3e-80: 250: 33.53
+	Hs
		298578 RAD17_HUMAN (4-508): 4.4e-81: 267: 21.96		RFC2_HUMAN (13-332): 8.84e-79: 246: 29.38
+	Ce
		916475 Q18841_CAEEL (5-512): 7e-77: 260: 13.84		RFC4_CAEEL (1-334): 2.05e-81: 252: 100.00
+	Hs
		769934 RFC1_HUMAN (2-512): 7.05e-88: 294: 13.29		RFC3_HUMAN (14-334): 1.13e-61: 202: 21.90
+	Dm
		773394 RFC1_DROME (9-496): 1.87e-74: 255: 12.90		Q9VX15_DROME (4-334): 1.79e-76: 240: 37.80
+	Sc
		800996 RFC1_YEAST (3-470): 3.79e-74: 252: 13.39		RFC2_YEAST (15-331): 1.68e-77: 243: 36.28
+	Dm
		773359 RFC1_DROME (9-496): 1.87e-74: 255: 12.90		RFC2_DROME (2-334): 1.96e-76: 239: 27.93
+	Sc
		800943 RFC1_YEAST (3-470): 3.79e-74: 252: 13.39		RFC3_YEAST (5-334): 1.14e-76: 240: 34.52
+	Dm
		773389 RFC1_DROME (9-496): 1.87e-74: 255: 12.90		Q9VKW3_DROME (5-329): 2.91e-75: 236: 31.71
+	Hs
		298581 RAD17_HUMAN (4-508): 4.4e-81: 267: 21.96		RFC3_HUMAN (14-334): 1.13e-61: 202: 21.90
+	Sc
		800994 RFC1_YEAST (3-470): 3.79e-74: 252: 13.39		RFC4_YEAST (15-331): 9.6e-68: 216: 30.92
+	Cj
		1076087 Q0P999_CAMJE (7-422): 5.98e-69: 231: 13.69		Q0P999_CAMJE (20-303): 3.87e-70: 228: 23.76
+	Sc
		796694 RFC1_YEAST (3-470): 3.79e-74: 252: 13.39		RFC5_YEAST (14-334): 2.83e-63: 206: 22.60
+	Dm
		773382 RFC1_DROME (9-496): 1.87e-74: 255: 12.90		Q9U9Q1_DROME (14-334): 5.24e-58: 192: 21.90
+	Ce
		1166107 Q18841_CAEEL (5-512): 7e-77: 260: 13.84		Q18547_CAEEL (14-333): 9.55e-53: 179: 20.34
+	Ec
		497817 FTSH_ECOLI (2-509): 8.84e-72: 242: 10.51		FTSH_ECOLI (11-329): 1.32e-52: 184: 13.71