HitPredict

Interactor 1: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7

Interactor 2: TAB2 (Q99K90)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	19843958, 31127032, 19955178, 17384642, 17158449, 19026643, 24270572
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 579 Mm			1 693
+	Hs
		201449 M3K7_HUMAN (1-579): 0: 540: 94.88		TAB2_HUMAN (1-693): 1.54e-111: 353: 94.66
+	Rn
		473815 M3K7_RAT (1-579): 0: 541: 95.05		TAB2_RAT (1-693): 2.75e-108: 345: 97.69
+	Mm
		1123042 M3K7_MOUSE (1-579): 0: 556: 100.00		TAB3_MOUSE (1-692): 2.05e-68: 239: 29.64
+	Hs
		201369 M3K7_HUMAN (1-579): 0: 540: 94.88		TAB3_HUMAN (1-692): 3.23e-70: 244: 30.26
+	Hs
		325752 M3K11_HUMAN (10-492): 9.58e-114: 360: 26.82		LATS1_HUMAN (2-574): 3.21e-24: 110: 11.55