HitPredict

Interactor 1: IRF9 (Q61179)
Interferon regulatory factor 9 (IRF-9) (IFN-alpha-responsive transcription factor subunit) (ISGF3 p48 subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF-3 gamma) (Transcriptional regulator ISGF3 subunit gamma)
Gene: IRF9

Interactor 2: Q9QXJ2 (Q9QXJ2)
Signal transducer and activator of transcription
Gene: Stat2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.80	0.702

Property	Details
Experiments	20211142, 15102471
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IRF-3~STAT_alpha
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 399 Mm			1 922
+	Hs
		838064 IRF8_HUMAN (8-394): 1.1e-148: 429: 33.66		STAT1_HUMAN (1-727): 0: 831: 40.48
+	Hs
		838058 IRF9_HUMAN (1-387): 9.7e-146: 421: 69.72		STAT1_HUMAN (1-727): 0: 831: 40.48
+	Hs
		827744 IRF9_HUMAN (1-387): 9.7e-146: 421: 69.72		STAT3_HUMAN (1-755): 0: 802: 36.48
+	Hs
		838087 IRF5_HUMAN (11-379): 2.41e-129: 382: 27.27		STAT1_HUMAN (1-727): 0: 831: 40.48
+	Hs
		1132021 IRF4_HUMAN (3-392): 7.35e-153: 441: 32.63		STAT4_HUMAN (1-740): 0: 756: 37.53
+	Hs
		913126 IRF9_HUMAN (1-387): 9.7e-146: 421: 69.72		STAT2_HUMAN (1-800): 0: 763: 70.06
+	Hs
		838152 IRF7_HUMAN (1-380): 1.68e-111: 337: 20.17		STAT1_HUMAN (1-727): 0: 831: 40.48
+	Hs
		913133 IRF5_HUMAN (11-379): 2.41e-129: 382: 27.27		STAT2_HUMAN (1-800): 0: 763: 70.06
+	Hs
		913154 IRF7_HUMAN (1-380): 1.68e-111: 337: 20.17		STAT2_HUMAN (1-800): 0: 763: 70.06
+	Hs
		533894 IRF1_HUMAN (11-217): 7.52e-64: 209: 24.17		STAT1_HUMAN (1-727): 0: 831: 40.48
+	Hs
		838235 IRF4_HUMAN (3-392): 7.35e-153: 441: 32.63		STAT6_HUMAN (1-880): 0: 576: 22.28
+	Hs
		533892 IRF1_HUMAN (11-217): 7.52e-64: 209: 24.17		STAT3_HUMAN (1-755): 0: 802: 36.48
+	Mm
		583133 IRF1_MOUSE (11-217): 7.45e-62: 204: 24.89		STAT3_MOUSE (1-755): 0: 803: 36.48
+	Hs
		838226 IRF9_HUMAN (1-387): 9.7e-146: 421: 69.72		STAT6_HUMAN (1-880): 0: 576: 22.28
+	Hs
		533906 IRF1_HUMAN (11-217): 7.52e-64: 209: 24.17		STAT2_HUMAN (1-800): 0: 763: 70.06
+	Hs
		533935 IRF1_HUMAN (11-217): 7.52e-64: 209: 24.17		STAT4_HUMAN (1-740): 0: 756: 37.53
+	Hs
		533904 IRF1_HUMAN (11-217): 7.52e-64: 209: 24.17		STA5B_HUMAN (1-787): 0: 722: 23.54
+	Hs
		533896 IRF1_HUMAN (11-217): 7.52e-64: 209: 24.17		STA5A_HUMAN (1-785): 0: 721: 23.26
+	Mm
		583134 IRF1_MOUSE (11-217): 7.45e-62: 204: 24.89		STA5A_MOUSE (1-794): 0: 721: 23.25
+	Hs
		533895 IRF1_HUMAN (11-217): 7.52e-64: 209: 24.17		STAT6_HUMAN (1-880): 0: 576: 22.28