Interactor 1: DNMT1 (P13864)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT)
Gene: DNMT1

Interactor 2: DNMT1 (P13864)
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC 2.1.1.37) (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT)
Gene: DNMT1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21311766
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BAH~BAH, BAH~DNA_methylase, DNA_methylase~DNA_methylase, DNA_methylase~DNMT1-RFD, DNA_methylase~zf-CXXC, zf-CXXC~zf-CXXC
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000792 - heterochromatin
GO:0001674 - female germ cell nucleus
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
and 39 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1620
Mm

1 1620
+ Hs
+ Xl
+ Dm
+ Xl
+ Hs
+ Mm
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024