HitPredict

Interactor 1: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Interactor 2: ARHG2 (Q92974)
Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40)
Gene: ARHGEF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RhoGEF~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0008270 - zinc ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 986
+	Hs
		1086369 TRI67_HUMAN (1-783): 0: 595: 100.00		AKP13_HUMAN (37-964): 7.01e-136: 454: 35.95
+	Hs
		1371071 TRI36_HUMAN (112-771): 4.44e-106: 343: 20.13		ARHG2_HUMAN (1-986): 0: 705: 100.00
+	Hs
		1254209 TRI67_HUMAN (1-783): 0: 595: 100.00		ARHGI_HUMAN (1-977): 6.72e-124: 411: 31.74
+	Hs
		1256043 TRI67_HUMAN (1-783): 0: 595: 100.00		VAV3_HUMAN (152-838): 1.22e-109: 361: 13.46
+	Hs
		1255867 TRI67_HUMAN (1-783): 0: 595: 100.00		ARHGC_HUMAN (23-973): 4.79e-101: 349: 16.47
+	Hs
		913659 TRI67_HUMAN (1-783): 0: 595: 100.00		VAV2_HUMAN (132-799): 1.51e-101: 340: 14.77
+	Hs
		177388 TRI67_HUMAN (1-783): 0: 595: 100.00		ARHGB_HUMAN (111-917): 1.06e-97: 339: 21.07
+	Hs
		1140178 TRI67_HUMAN (1-783): 0: 595: 100.00		ARHG6_HUMAN (32-797): 1.7e-101: 337: 11.75
+	Hs
		1121959 TRI67_HUMAN (1-783): 0: 595: 100.00		ARHG7_HUMAN (32-779): 1.14e-94: 319: 12.53
+	Hs
		213362 TRI67_HUMAN (1-783): 0: 595: 100.00		ARHG9_HUMAN (162-603): 9.43e-95: 311: 12.92
+	Hs
		238820 TRI67_HUMAN (1-783): 0: 595: 100.00		KALRN_HUMAN (224-970): 4.71e-87: 309: 12.83
+	Hs
		1254908 TRI67_HUMAN (1-783): 0: 595: 100.00		ARHG1_HUMAN (31-760): 1.57e-87: 302: 21.18
+	Hs
		299557 TRI67_HUMAN (1-783): 0: 595: 100.00		TRIO_HUMAN (224-976): 3.48e-75: 273: 12.76
+	Hs
		1154110 TRI67_HUMAN (1-783): 0: 595: 100.00		ITSN1_HUMAN (222-600): 2.11e-69: 255: 22.73
+	Hs
		1140194 TRI54_HUMAN (198-528): 1.12e-73: 245: 20.71		ARHG6_HUMAN (32-797): 1.7e-101: 337: 11.75
+	Hs
		213352 RO52_HUMAN (112-378): 2.43e-12: 72: 9.29		ARHG9_HUMAN (162-603): 9.43e-95: 311: 12.92
+	Hs
		572235 TRI27_HUMAN (104-639): 1.21e-12: 73.2: 12.20		ARHG3_HUMAN (115-602): 2.32e-56: 205: 17.50