HitPredict

Interactor 1: ENAH (Q8N8S7)
Protein enabled homolog
Gene: ENAH

Interactor 2: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	17101133
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030027 - lamellipodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 591 Hs			1 366
+	Hs
		1449301 HOME2_HUMAN (1-299): 1.96e-65: 219: 18.75		ABI3_HUMAN (1-366): 5.41e-88: 271: 100.00
+	Hs
		1295224 HOME1_HUMAN (1-285): 2.85e-39: 149: 15.64		ABI3_HUMAN (1-366): 5.41e-88: 271: 100.00
+	Mm
		976077 TNIK_MOUSE (90-575): 1.05e-33: 139: 14.08		ABI2_MOUSE (1-363): 1.19e-86: 270: 34.40
+	Hs
		1449321 HOME3_HUMAN (3-274): 2.32e-31: 127: 19.42		ABI3_HUMAN (1-366): 5.41e-88: 271: 100.00
+	Mm
		1298233 MINK1_MOUSE (113-575): 8.8e-40: 158: 16.21		ABI1_MOUSE (1-314): 3.09e-64: 213: 34.35
+	Hs
		1331368 ENAH_HUMAN (1-591): 2.14e-77: 258: 100.00		ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18
+	Hs
		1316675 ENAH_HUMAN (1-591): 2.14e-77: 258: 100.00		ABI1_HUMAN (124-363): 6.4e-21: 95.9: 24.49
+	Mm
		1013665 TNIK_MOUSE (90-575): 1.05e-33: 139: 14.08		ABI1_MOUSE (1-314): 3.09e-64: 213: 34.35
+	Hs
		302182 SPRE1_HUMAN (2-314): 1.72e-57: 201: 18.58		NEBL_HUMAN (13-363): 2.11e-35: 139: 14.44
+	Hs
		1124672 CTTB2_HUMAN (87-571): 1.35e-43: 169: 13.08		SRC8_HUMAN (40-363): 4.99e-43: 158: 16.12
+	Hs
		302210 HOME3_HUMAN (3-274): 2.32e-31: 127: 19.42		NEBL_HUMAN (13-363): 2.11e-35: 139: 14.44
+	Mm
		1013600 TNIK_MOUSE (90-575): 1.05e-33: 139: 14.08		SH3G2_MOUSE (265-363): 3.48e-27: 111: 24.75
+	Hs
		1295191 HOME1_HUMAN (1-285): 2.85e-39: 149: 15.64		ABI1_HUMAN (124-363): 6.4e-21: 95.9: 24.49
+	Hs
		1449319 HOME3_HUMAN (3-274): 2.32e-31: 127: 19.42		ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18
+	Hs
		1154162 ITSN1_HUMAN (124-263): 2.98e-29: 125: 37.59		SH3G2_HUMAN (265-363): 7.93e-26: 108: 23.76
+	Hs
		1316711 HOME3_HUMAN (3-274): 2.32e-31: 127: 19.42		ABI1_HUMAN (124-363): 6.4e-21: 95.9: 24.49
+	Hs
		987773 MINK1_HUMAN (113-575): 1.26e-34: 142: 15.12		GRB2_HUMAN (312-363): 4.05e-14: 72.7: 28.30
+	Hs
		1154182 ITSN1_HUMAN (124-263): 2.98e-29: 125: 37.59		ITSN2_HUMAN (306-365): 5.4e-13: 72.7: 37.50
+	Hs
		169499 HGS_HUMAN (90-385): 6.34e-28: 120: 22.22		GRB2_HUMAN (312-363): 4.05e-14: 72.7: 28.30
+	Hs
		1154087 ITSN1_HUMAN (124-263): 2.98e-29: 125: 37.59		ITSN1_HUMAN (205-363): 5.28e-10: 63.2: 15.85