HitPredict

Interactor 1: KRA57 (Q6L8G8)
Keratin-associated protein 5-7 (Keratin-associated protein 5-3) (Keratin-associated protein 5.3) (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7)
Gene: KRTAP5-7

Interactor 2: IGSF8 (Q969P0)
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)
Gene: IGSF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 613
+	Hs
		1216367 KRA13_HUMAN (10-162): 5.74e-19: 80.5: 22.22		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		889857 KR109_HUMAN (18-164): 1.34e-16: 76.7: 24.84		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		888954 KR103_HUMAN (55-162): 1.53e-15: 72.8: 30.56		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		889614 KR108_HUMAN (27-162): 1.13e-13: 68.2: 23.93		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		889356 KR107_HUMAN (39-163): 3.41e-13: 67.8: 27.78		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		889217 KR104_HUMAN (17-160): 8.29e-12: 64: 31.17		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		1281779 KR412_HUMAN (54-154): 1.31e-09: 56.3: 34.95		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		991639 KRA11_HUMAN (6-135): 6.09e-09: 54.3: 21.52		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Dm
		246771 TENM_DROME (2-163): 2.8e-29: 114: 18.31		FGFR2_DROME (104-599): 6.05e-13: 74.3: 15.91