HitPredict

Interactor 1: Q8R2E7 (Q8R2E7)
FAS-associated death domain protein (FAS-associating death domain-containing protein)
Gene: Fadd

Interactor 2: CASP8 (Q9JHX4)
Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
Gene: CASP8

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 19001025
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DED~DED
Common GO terms GO:0005123 - death receptor binding
GO:0005164 - tumor necrosis factor receptor binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 20 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 208
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Service provided by Combinatics, Japan

Last updated: 11Aug2025