HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: PF21B (Q96EK2)
PHD finger protein 21B
Gene: PHF21B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Hist_deacetyl~PHD
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 531
+	Hs
		1368181 HDAC2_HUMAN (1-488): 0: 707: 100.00		KDM5B_HUMAN (79-519): 1.42e-70: 247: 13.09
+	Hs
		711837 HDAC2_HUMAN (1-488): 0: 707: 100.00		KDM5A_HUMAN (79-519): 2.93e-67: 238: 13.58
+	Hs
		833763 HDAC2_HUMAN (1-488): 0: 707: 100.00		KDM5C_HUMAN (78-518): 1.7e-65: 232: 13.45
+	Hs
		180886 HDAC2_HUMAN (1-488): 0: 707: 100.00		TIF1A_HUMAN (5-502): 4.22e-64: 227: 13.45
+	Hs
		1368040 HDAC2_HUMAN (1-488): 0: 707: 100.00		PF21A_HUMAN (41-531): 1.81e-52: 191: 28.65
+	Mm
		59100 HDAC2_MOUSE (1-488): 0: 704: 99.39		CHD5_MOUSE (133-525): 4.19e-48: 182: 15.73
+	Hs
		1351278 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD5_HUMAN (131-525): 9e-43: 165: 15.89
+	Hs
		355572 HDAC2_HUMAN (1-488): 0: 707: 100.00		NSD2_HUMAN (87-515): 3.99e-41: 160: 12.72
+	Hs
		1088484 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD3_HUMAN (125-525): 6.74e-38: 151: 12.90
+	Hs
		1132869 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD4_HUMAN (301-481): 3.05e-37: 149: 20.51
+	Dm
		1374486 HDAC1_DROME (5-472): 0: 653: 77.92		KDM5_DROME (79-518): 3.69e-55: 202: 13.36
+	Mm
		1000005 HDAC2_MOUSE (1-488): 0: 704: 99.39		Q5DTP7_MOUSE (301-481): 2.12e-37: 149: 20.51
+	Hs
		1368204 HDAC2_HUMAN (1-488): 0: 707: 100.00		ZMYD8_HUMAN (250-449): 2.19e-36: 146: 19.00
+	Dm
		1374477 HDAC1_DROME (5-472): 0: 653: 77.92		Q9VDK5_DROME (94-494): 7.51e-45: 171: 13.79
+	Dm
		72172 HDAC1_DROME (5-472): 0: 653: 77.92		A8WHL4_DROME (94-494): 2.71e-43: 167: 13.30
+	Dm
		356804 HDAC1_DROME (5-472): 0: 653: 77.92		CHDM_DROME (120-525): 5.04e-43: 166: 13.29
+	Hs
		1086799 HDAC2_HUMAN (1-488): 0: 707: 100.00		BPTF_HUMAN (320-396): 2.32e-14: 78.7: 33.77
+	Hs
		231157 HDAC2_HUMAN (1-488): 0: 707: 100.00		AIRE_HUMAN (351-403): 2.61e-14: 77.6: 41.51
+	Hs
		1368065 HDAC2_HUMAN (1-488): 0: 707: 100.00		PHF12_HUMAN (337-405): 5.08e-13: 74.1: 35.62
+	Dm
		1374503 HDAC1_DROME (5-472): 0: 653: 77.92		Q9W410_DROME (162-394): 4.41e-16: 83.7: 16.24