Interactor 1: OPA1 (O60313)
Dynamin-like GTPase OPA1, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1) [Cleaved into: Dynamin-like GTPase OPA1, long form (L-OPA1); Dynamin-like GTPase OPA1, short form (S-OPA1)]
Gene: OPA1

Interactor 2: PARL (Q9H300)
Presenilin-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]
Gene: PARL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 31617661
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0008053 - mitochondrial fusion
GO:0090201 - negative regulation of release of cytochrome c from mitochondria
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 960
Hs

1 379
+ Mm
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024