Interactor 1: RGS12 (O14924)
Regulator of G-protein signaling 12 (RGS12)
Gene: RGS12
Interactor 2: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.924 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 11387333, 33961781, unassigned3799 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | G-alpha~GoLoco, G-alpha~RGS |
| Common GO terms | GO:0003924 - GTPase activity GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
