HitPredict

Interactor 1: AXIN1 (O35625)
Axin-1 (Axis inhibition protein 1) (Protein Fused)
Gene: AXIN1

Interactor 2: GSK3B (Q9WV60)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 25331900, 10318824, 18316368, 14734535, 22682247, 21242974, 19581931
Identification Methods affinity chromatography technology, pull down, biochemical, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RGS
Common GO terms GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 12 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 863
Mm

1 420
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024