Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: ITA5 (P08648)
Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]
Gene: ITGA5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 33961781, 20643357, 26456826, 25237190, 7681433, 1532572, 19738201, 22451694
Identification Methods affinity chromatography technology, pull down, enzyme linked immunosorbent assay, anti tag coimmunoprecipitation, surface plasmon resonance, cross-linking study
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007044 - cell-substrate junction assembly
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 2477
Hs

1 1049
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024