HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RN19B (Q6ZMZ0)
E3 ubiquitin-protein ligase RNF19B (EC 2.3.2.31) (IBR domain-containing protein 3) (Natural killer lytic-associated molecule) (RING finger protein 19B)
Gene: RNF19B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16196087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IBR~ubiquitin
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 732
+	Hs
		476630 UBC_HUMAN (1-685): 0: 846: 100.00		ARI1_HUMAN (92-346): 4.15e-78: 262: 23.28
+	Hs
		475976 UBC_HUMAN (1-685): 0: 846: 100.00		R144B_HUMAN (113-380): 9.6e-81: 261: 24.63
+	Hs
		475494 UBC_HUMAN (1-685): 0: 846: 100.00		R144A_HUMAN (114-380): 9.13e-77: 250: 26.84
+	Hs
		312458 UBC_HUMAN (1-685): 0: 846: 100.00		ARI2_HUMAN (106-346): 5.48e-72: 244: 22.13
+	Hs
		476496 UBC_HUMAN (1-685): 0: 846: 100.00		AKIB1_HUMAN (73-343): 2.38e-66: 239: 21.16
+	Hs
		475069 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RN19B_HUMAN (1-732): 0: 976: 100.00
+	Hs
		476320 UBC_HUMAN (1-685): 0: 846: 100.00		HOIL1_HUMAN (55-317): 4.28e-60: 212: 25.23
+	Hs
		226335 UBC_HUMAN (1-685): 0: 846: 100.00		PRKN_HUMAN (83-330): 2.95e-55: 198: 20.30
+	Dm
		477528 UBIQP_DROME (1-610): 0: 752: 99.84		LUBEL_DROME (118-321): 1.46e-45: 178: 22.32
+	Dm
		1214032 Q9W418_DROME (229-685): 0: 557: 99.78		LUBEL_DROME (118-321): 1.46e-45: 178: 22.32
+	Sc
		477225 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		HEL1_YEAST (115-345): 4.84e-62: 219: 24.79
+	Hs
		312457 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		ARI2_HUMAN (106-346): 5.48e-72: 244: 22.13
+	Hs
		227107 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		PRKN_HUMAN (83-330): 2.95e-55: 198: 20.30
+	Hs
		475094 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		CUL9_HUMAN (108-346): 9.14e-63: 230: 24.59
+	Rn
		1144287 UBC_RAT (1-108): 1.27e-29: 127: 90.74		PRKN_RAT (83-330): 1.5e-55: 199: 20.30
+	Mm
		477054 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		HOIL1_MOUSE (55-317): 5.33e-55: 198: 24.47
+	Hs
		226251 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PRKN_HUMAN (83-330): 2.95e-55: 198: 20.30
+	Hs
		171468 UBD_HUMAN (155-304): 5.41e-28: 112: 32.05		PRKN_HUMAN (83-330): 2.95e-55: 198: 20.30
+	Hs
		226334 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		PRKN_HUMAN (83-330): 2.95e-55: 198: 20.30