HitPredict

Interactor 1: PRPS1 (P60891)
Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I)
Gene: PRPS1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 318 Hs			1 779
+	Hs
		515941 PRPS2_HUMAN (1-318): 7.43e-180: 500: 95.28		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		596709 PRPS3_HUMAN (1-318): 1.07e-176: 492: 94.34		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		225902 KPRB_HUMAN (3-318): 4.84e-137: 394: 44.00		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1055355 KPRA_HUMAN (3-318): 6.17e-132: 381: 42.98		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		515971 PRPS2_HUMAN (1-318): 7.43e-180: 500: 95.28		TBD2B_HUMAN (53-512): 3.31e-51: 195: 17.57
+	Hs
		596387 PRPS1_HUMAN (1-318): 0: 507: 100.00		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		515801 PRPS2_HUMAN (1-318): 7.43e-180: 500: 95.28		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		893409 PRPS1_HUMAN (1-318): 0: 507: 100.00		SESQ1_HUMAN (40-169): 5.2e-35: 135: 28.03
+	Hs
		225883 KPRB_HUMAN (3-318): 4.84e-137: 394: 44.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		225843 KPRB_HUMAN (3-318): 4.84e-137: 394: 44.00		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		596402 KPRA_HUMAN (3-318): 6.17e-132: 381: 42.98		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		225903 KPRB_HUMAN (3-318): 4.84e-137: 394: 44.00		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90