HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RN168 (Q8IYW5)
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168)
Gene: RNF168

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	28240985, 31699778, 38803224, 22266820, 26503038, 28406400, 29330428, 22742833
Identification Methods	pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 571
+	Hs
		476061 UBC_HUMAN (1-685): 0: 846: 100.00		RN169_HUMAN (13-432): 1.06e-29: 126: 23.85
+	Hs
		475096 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Mm
		476872 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN168_MOUSE (1-568): 5.42e-77: 255: 63.80
+	Hs
		924095 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05