Interactor 1: GNAO (P09471)
Guanine nucleotide-binding protein G(o) subunit alpha (EC 3.6.5.-)
Gene: GNAO1

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.633

The method score is based on:

Property Details
Experiments 32505358, 35271311, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003924 - GTPase activity
GO:0005737 - cytoplasm
GO:0005834 - heterotrimeric G-protein complex
GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 354
Hs

1 340
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 11Aug2025