HitPredict

Interactor 1: UBA6 (A0AVT1)
Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)
Gene: UBA6

Interactor 2: UB2G2 (P60604)
Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)
Gene: UBE2G2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17597759
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 165
+	Hs
		48347 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03
+	Hs
		48351 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03
+	Hs
		48349 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D3_HUMAN (4-164): 4.3e-71: 212: 34.78
+	Hs
		647684 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D4_HUMAN (4-164): 1.27e-73: 218: 36.03
+	Hs
		647506 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03
+	Hs
		647533 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03
+	Hs
		647521 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D3_HUMAN (4-164): 4.3e-71: 212: 34.78
+	Hs
		647520 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2G2_HUMAN (1-165): 5.28e-70: 210: 100.00
+	Hs
		647529 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2G1_HUMAN (4-164): 3.81e-68: 205: 50.00
+	Hs
		647502 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2A_HUMAN (1-162): 1.27e-66: 201: 38.89
+	Oc
		1177142 UBA1_RABIT (1-1045): 0: 1139: 41.11		UB2R2_RABIT (4-158): 9.25e-45: 149: 50.00
+	Hs
		647586 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2R2_HUMAN (4-158): 9.25e-45: 149: 50.00
+	Hs
		647501 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2R1_HUMAN (4-159): 1.55e-43: 145: 49.08
+	Hs
		647537 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2B_HUMAN (1-162): 1.26e-35: 122: 38.89
+	Sp
		314596 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC4_SCHPO (4-163): 2.99e-70: 210: 34.38
+	Sp
		122416 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC7_SCHPO (1-165): 3.87e-69: 208: 66.87
+	Dm
		1344410 Q8T0L3_DROME (21-1045): 0: 990: 40.89		Q8SYG3_DROME (1-164): 1.36e-68: 207: 51.52
+	Sp
		314600 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC15_SCHPO (9-151): 3.21e-55: 173: 56.64
+	Sp
		314595 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC2_SCHPO (1-162): 3.82e-36: 124: 37.65
+	Sc
		438521 UBA1_YEAST (24-1046): 0: 979: 40.52		UBC2_YEAST (1-162): 1.08e-33: 118: 37.65