Interactor 1: MK03 (P27361)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: MAPK3

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 12624094, 12840032
Identification Methods affinity chromatography technology, phosphatase assay
Interaction Type physical association, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0035556 - intracellular signal transduction
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 379
Hs

1 309
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024