HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: UBP8 (P40818)
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
Gene: USP8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	23333852
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding GO:0090263 - positive regulation of canonical Wnt signaling pathway GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 1118
+	Hs
		523210 SRC_HUMAN (1-536): 0: 651: 100.00		UBP22_HUMAN (744-1109): 3.1e-111: 358: 27.72
+	Hs
		846546 BLK_HUMAN (45-531): 1.62e-179: 516: 57.58		UBP22_HUMAN (744-1109): 3.1e-111: 358: 27.72
+	Hs
		64203 BLK_HUMAN (45-531): 1.62e-179: 516: 57.58		UBP27_HUMAN (744-1109): 3.62e-106: 341: 26.80
+	Hs
		522952 SRC_HUMAN (1-536): 0: 651: 100.00		UBP4_HUMAN (964-1106): 5.42e-33: 140: 44.06
+	Hs
		523072 SRC_HUMAN (1-536): 0: 651: 100.00		UBP32_HUMAN (957-1042): 1.54e-14: 80.9: 42.53
+	Hs
		411649 LCK_HUMAN (75-534): 0: 552: 58.48		UBP11_HUMAN (964-1106): 7.58e-34: 143: 44.90