HitPredict

Interactor 1: CI (P19538)
Transcriptional activator cubitus interruptus (Transcriptional activator ci) (ci form of 155 kDa) (ci-155) (ci full-length protein) (ciFL) [Cleaved into: Transcriptional repressor cubitus interruptus (Transcriptional repressor ci) (ci C-terminally truncated form) (ci form of 75 kDa) (ci-75)]
Gene: CI

Interactor 2: CI (P19538)
Transcriptional activator cubitus interruptus (Transcriptional activator ci) (ci form of 155 kDa) (ci-155) (ci full-length protein) (ciFL) [Cleaved into: Transcriptional repressor cubitus interruptus (Transcriptional repressor ci) (ci C-terminally truncated form) (ci form of 75 kDa) (ci-75)]
Gene: CI

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.837

The method score is based on:

Property Details
Experiments 19955409, 15710747
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, two hybrid, anti tag coimmunoprecipitation, two hybrid fragment pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C2H2~zf-C2H2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 31 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1397
Dm

1 1397
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Last updated: 15 Jul 2024