Interactor 1: NCF2 (P19878)
Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox)
Gene: NCF2

Interactor 2: NCF4 (Q15080)
Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (SH3 and PX domain-containing protein 4) (p40-phox) (p40phox)
Gene: NCF4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 9083043, 12887891, 12813044, 11893732, 11796733, 11483497, 16782902, 9490029, 8760383, 16297854
Identification Methods two hybrid, x-ray crystallography, affinity chromatography technology, pull down, filter binding, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, PB1~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006909 - phagocytosis
GO:0016020 - membrane
GO:0016176 - superoxide-generating NADPH oxidase activator activity
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024