HitPredict

Interactor 1: MLR (P18432)
Myosin regulatory light chain 2 (MLC-2)
Gene: Mlc2

Interactor 2: MYSP2 (P35416)
Paramyosin, short form (Miniparamyosin)
Gene: Prm

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030239 - myofibril assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 222 Dm			1 640
+	Hs
		169065 ML12B_HUMAN (60-219): 3.73e-68: 208: 40.12		MYH10_HUMAN (8-636): 9.03e-29: 125: 14.71
+	Hs
		169064 ML12B_HUMAN (60-219): 3.73e-68: 208: 40.12		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		618654 ML12A_HUMAN (61-219): 1.35e-67: 207: 40.37		MYH10_HUMAN (8-636): 9.03e-29: 125: 14.71
+	Hs
		618653 ML12A_HUMAN (61-219): 1.35e-67: 207: 40.37		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Hs
		666741 MYL9_HUMAN (61-219): 2.52e-67: 206: 39.13		MYH10_HUMAN (8-636): 9.03e-29: 125: 14.71
+	Hs
		666740 MYL9_HUMAN (61-219): 2.52e-67: 206: 39.13		MYH9_HUMAN (2-638): 1.09e-28: 124: 13.61
+	Mm
		1223376 Q6ZWQ9_MOUSE (48-219): 2.78e-68: 208: 37.93		MYH10_MOUSE (130-640): 1.17e-24: 112: 13.85
+	Hs
		169066 ML12B_HUMAN (60-219): 3.73e-68: 208: 40.12		MYH11_HUMAN (151-636): 2.1e-24: 111: 10.94
+	Hs
		618655 ML12A_HUMAN (61-219): 1.35e-67: 207: 40.37		MYH11_HUMAN (151-636): 2.1e-24: 111: 10.94
+	Dm
		823778 SQH_DROME (48-220): 2.87e-63: 196: 38.42		MYSN_DROME (3-640): 1.55e-26: 118: 13.10
+	Hs
		169114 ML12B_HUMAN (60-219): 3.73e-68: 208: 40.12		MYH14_HUMAN (293-616): 1.2e-22: 105: 25.62
+	Hs
		618709 ML12A_HUMAN (61-219): 1.35e-67: 207: 40.37		MYH14_HUMAN (293-616): 1.2e-22: 105: 25.62
+	Hs
		169045 ML12B_HUMAN (60-219): 3.73e-68: 208: 40.12		MYH7_HUMAN (7-421): 6.51e-17: 87.3: 12.77
+	Dm
		432167 MLR_DROME (1-222): 2.65e-62: 195: 100.00		MYSA_DROME (3-640): 2.76e-17: 88.5: 10.31
+	Hs
		169165 ML12B_HUMAN (60-219): 3.73e-68: 208: 40.12		MYH15_HUMAN (354-640): 1.25e-11: 70.4: 12.97
+	Hs
		533985 MLRV_HUMAN (53-217): 1.4e-59: 186: 37.50		MYH1_HUMAN (9-498): 7.8e-17: 87: 10.10
+	Mm
		906631 MLRV_MOUSE (53-217): 4.11e-58: 182: 36.31		MYH6_MOUSE (14-472): 1.27e-15: 83.1: 9.76
+	Ce
		386945 MLR1_CAEEL (63-221): 8.11e-21: 87: 40.12		MYO4_CAEEL (69-638): 6.13e-14: 77.7: 14.01
+	Ce
		386946 MLR2_CAEEL (63-221): 1.46e-20: 86.7: 39.51		MYO4_CAEEL (69-638): 6.13e-14: 77.7: 14.01
+	Ce
		386956 MLR1_CAEEL (63-221): 8.11e-21: 87: 40.12		MYO1_CAEEL (123-609): 4.47e-13: 74.8: 12.35