Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Interactor 2: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.875

The method score is based on:

Property Details
Experiments 14755638, 22940862, 24351022, 25215493
Identification Methods two hybrid, affinity chromatography technology, biochemical, molecular sieving
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~CDC48_2, AAA~CDC48_N, AAA_lid_3~AAA_lid_3, AAA_lid_3~CDC48_2, AAA_lid_3~CDC48_N, CDC48_2~CDC48_2, CDC48_2~CDC48_N, CDC48_N~CDC48_N
Common GO terms GO:0000837 - Doa10p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
and 36 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 835
Sc

1 835
+ Dm
+ At
+ Rn
+ Hs
+ Mm
+ Ce
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sp
+ Sp
+ Hs

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Last updated: 15 Jul 2024