HitPredict

Interactor 1: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 156
+	Hs
		710605 EPHA3_HUMAN (22-975): 0: 1100: 42.49		CDN2A_HUMAN (1-156): 9.11e-52: 163: 100.00
+	Hs
		710822 EPHB2_HUMAN (27-975): 0: 1109: 40.81		ANK3_HUMAN (3-153): 3.24e-36: 133: 16.94
+	Hs
		710109 EPHA2_HUMAN (24-976): 0: 1053: 49.90		CDN2A_HUMAN (1-156): 9.11e-52: 163: 100.00
+	Hs
		710110 EPHA2_HUMAN (24-976): 0: 1053: 49.90		CDN2B_HUMAN (3-136): 4.73e-52: 163: 81.34
+	Hs
		710207 EPHA2_HUMAN (24-976): 0: 1053: 49.90		ANK3_HUMAN (3-153): 3.24e-36: 133: 16.94
+	Hs
		710576 EPHA2_HUMAN (24-976): 0: 1053: 49.90		ANR26_HUMAN (3-155): 9.54e-35: 129: 18.71
+	Hs
		710812 EPHB2_HUMAN (27-975): 0: 1109: 40.81		ANK2_HUMAN (3-63): 3.65e-14: 70.7: 24.19
+	Hs
		640281 EPHA1_HUMAN (1-976): 0: 1103: 100.00		TANC1_HUMAN (56-154): 1.19e-14: 71.9: 21.00
+	Hs
		640132 EPHA1_HUMAN (1-976): 0: 1103: 100.00		DAPK1_HUMAN (69-155): 1.65e-14: 71.5: 24.14
+	Hs
		931913 EPHA5_HUMAN (3-975): 0: 1109: 41.71		KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48
+	Hs
		332386 EPHA1_HUMAN (1-976): 0: 1103: 100.00		TNKS1_HUMAN (49-142): 1.95e-13: 68.6: 25.26
+	Hs
		640288 EPHA1_HUMAN (1-976): 0: 1103: 100.00		TNKS2_HUMAN (8-136): 1.51e-11: 63.2: 21.05
+	Hs
		710670 EPHA3_HUMAN (22-975): 0: 1100: 42.49		KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48
+	Hs
		710562 EPHA2_HUMAN (24-976): 0: 1053: 49.90		ANR50_HUMAN (26-148): 7.13e-27: 106: 27.64
+	Hs
		710111 EPHA2_HUMAN (24-976): 0: 1053: 49.90		CDN2C_HUMAN (21-135): 9.52e-26: 97.8: 28.21
+	Hs
		710561 EPHA2_HUMAN (24-976): 0: 1053: 49.90		KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48
+	Hs
		710530 EPHA2_HUMAN (24-976): 0: 1053: 49.90		RAI14_HUMAN (1-64): 1e-11: 63.4: 21.21
+	Hs
		720361 UFO_HUMAN (274-914): 3.8e-156: 485: 25.11		KDIS_HUMAN (86-156): 3.21e-12: 65: 19.48
+	Hs
		1051082 FAK1_HUMAN (630-884): 1.18e-63: 236: 45.88		ANR26_HUMAN (3-155): 9.54e-35: 129: 18.71