HitPredict

Interactor 1: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26725010, 29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 483 Hs			1 582
+	Hs
		757639 IF4A3_HUMAN (58-464): 7.79e-170: 486: 35.70		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116430 DDX17_HUMAN (24-467): 7.5e-145: 433: 27.31		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		571479 DDX5_HUMAN (15-467): 1.7e-142: 423: 25.70		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Dm
		597046 DDX6_DROME (47-471): 1.33e-158: 459: 71.77		PABP_DROME (28-516): 8.3e-58: 206: 12.35
+	Hs
		516391 IF4A3_HUMAN (58-464): 7.79e-170: 486: 35.70		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		403089 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		640620 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11
+	Hs
		640464 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516363 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		640517 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		571585 DDX5_HUMAN (15-467): 1.7e-142: 423: 25.70		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Dm
		582589 DDX6_DROME (47-471): 1.33e-158: 459: 71.77		SXL_DROME (59-259): 1.13e-24: 107: 20.29
+	Hs
		1271680 DDX17_HUMAN (24-467): 7.5e-145: 433: 27.31		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Mm
		857323 DDX17_MOUSE (24-467): 2.89e-145: 432: 27.31		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Dm
		612686 DDX6_DROME (47-471): 1.33e-158: 459: 71.77		LARP_DROME (38-120): 1.58e-13: 76.1: 35.23
+	Mm
		857351 Q8BTS0_MOUSE (15-467): 2.86e-142: 423: 25.92		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		640514 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		640489 DDX6_HUMAN (1-483): 4.05e-151: 441: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		1077436 DDX17_HUMAN (24-467): 7.5e-145: 433: 27.31		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		571469 DDX5_HUMAN (15-467): 1.7e-142: 423: 25.70		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50