Interactor 1: SMCA1 (P28370)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 (SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A1) (EC 3.6.4.-) (Global transcription activator SNF2L1) (Nucleosome-remodeling factor subunit SNF2L) (SNF2L) (SNF2 related chromatin remodeling ATPase 1)
Gene: SMARCA1

Interactor 2: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 26030138
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HAND~SNF2-rel_dom, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom, SNF2-rel_dom~SNF2-rel_dom
Common GO terms GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1042
Hs

1 1493
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025