HitPredict

Interactor 1: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 27248496, 33961781, 19862764
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 719 Hs			1 103
+	Hs
		708595 MCM5_HUMAN (6-716): 0: 682: 27.61		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356303 MCM5_YEAST (5-716): 0: 666: 27.77		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		832321 MCM2_HUMAN (8-690): 0: 643: 28.13		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356306 MCM4_YEAST (7-703): 0: 658: 29.69		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		708413 MCM4_HUMAN (5-700): 0: 636: 31.52		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917263 MCM6_HUMAN (3-715): 0: 623: 28.05		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356602 MCM6_YEAST (9-704): 0: 616: 29.69		H4_YEAST (18-103): 6.13e-41: 132: 90.70