HitPredict

Interactor 1: PTN3 (P26045)
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Gene: PTPN3

Interactor 2: SHKB1 (Q8TBC3)
SH3KBP1-binding protein 1 (SETA-binding protein 1)
Gene: SHKBP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.636

Property	Details
Experiments	27880917, 27432908, 28330616, 28675297
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 707
+	Hs
		708859 PTN4_HUMAN (1-913): 0: 811: 50.11		SHKB1_HUMAN (1-707): 0: 1176: 100.00
+	Hs
		684048 PTN3_HUMAN (1-913): 0: 865: 100.00		KCTD3_HUMAN (3-657): 0: 991: 63.58
+	Hs
		1090209 PTN13_HUMAN (12-634): 3.58e-75: 272: 17.80		KCTD3_HUMAN (3-657): 0: 991: 63.58
+	Hs
		708858 PTN4_HUMAN (1-913): 0: 811: 50.11		KCD17_HUMAN (19-118): 1.59e-34: 135: 45.10
+	Hs
		1370939 E41LA_HUMAN (26-494): 5.96e-125: 395: 28.48		KCNB2_HUMAN (5-232): 3.48e-54: 202: 16.06
+	Hs
		643069 E41L1_HUMAN (8-666): 1.06e-128: 410: 23.09		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Hs
		643082 E41L5_HUMAN (10-660): 5.72e-129: 407: 22.00		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Hs
		643153 E41L3_HUMAN (21-661): 9.86e-124: 403: 24.11		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Hs
		217383 E41L2_HUMAN (19-550): 5.1e-121: 393: 24.06		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Mm
		1296494 E41L1_MOUSE (8-665): 1.08e-128: 410: 23.16		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Hs
		538870 EPB41_HUMAN (7-534): 3.61e-119: 385: 24.39		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45
+	Mm
		1296463 E41L3_MOUSE (20-646): 2.02e-125: 403: 23.09		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Hs
		614716 PTPRA_HUMAN (322-902): 9.6e-96: 321: 18.39		KCNB2_HUMAN (5-232): 3.48e-54: 202: 16.06
+	Mm
		266876 E41L2_MOUSE (7-545): 5.08e-117: 382: 24.73		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Mm
		1296404 E41LB_MOUSE (8-462): 1.33e-119: 375: 23.85		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Mm
		72842 PTPRS_MOUSE (180-902): 3e-100: 346: 18.41		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Hs
		658964 PTPRE_HUMAN (305-902): 1.53e-85: 290: 16.88		KCNB1_HUMAN (2-232): 7.94e-52: 195: 16.27
+	Hs
		595029 PTPRA_HUMAN (322-902): 9.6e-96: 321: 18.39		KCNA2_HUMAN (1-231): 1.22e-42: 163: 14.23
+	Mm
		611456 PTPRA_MOUSE (353-902): 1.77e-95: 320: 18.82		BACD1_MOUSE (5-150): 4.88e-36: 140: 25.68
+	Hs
		642833 PTN13_HUMAN (12-634): 3.58e-75: 272: 17.80		KCNA3_HUMAN (3-228): 1.2e-42: 164: 15.45