HitPredict

Interactor 1: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Interactor 2: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 25313033, 31728581, 19106085, 25342810, 23499444, 26255844, 26686640, 27397685, 25172955, 32075754, 19661920, 19896182, 37968396, 38776358, 39838174, 22433841, 23499531, 24805245
Identification Methods biochemical, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM4_WHD, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM~MCM5_C, MCM5_C~MCM_lid, MCM4_WHD~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 13 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 775
Sc

1 933
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Last updated: 11Aug2025