Interactor 1: KPR1 (P32895)
Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 1)
Gene: PRS1
Interactor 2: KPR3 (P38689)
Ribose-phosphate pyrophosphokinase 3 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 3)
Gene: PRS3
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.967 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17892321, 11283351, 16429126, 30649305, 37968396, 10212224, 18719252, 31851481 |
| Identification Methods | anti tag coimmunoprecipitation, two hybrid pooling approach, affinity chromatography technology, two hybrid, cross-linking study, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pribosyl_synth~Pribosyl_synth, Pribosyl_synth~Pribosyltran_N, Pribosyltran_N~Pribosyltran_N |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0002189 - ribose phosphate diphosphokinase complex GO:0004749 - ribose phosphate diphosphokinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm and 4 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
