HitPredict

Interactor 1: FGD1 (P52734)
FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)
Gene: FGD1

Interactor 2: SRC8 (Q60598)
Src substrate cortactin
Gene: Cttn

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 12913069
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, filter binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001726 - ruffle
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0030027 - lamellipodium
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 960
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Last updated: 11Aug2025