HitPredict

Interactor 1: C9J2V2 (C9J2V2)
NF-kappa-B essential modulator (IkB kinase-associated protein 1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Interactor 2: M3K14 (Q99558)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)
Gene: MAP3K14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30833792
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 407 Hs			1 947
+	Hs
		1405275 NEMO_HUMAN (1-407): 4.37e-54: 186: 100.00		M3K14_HUMAN (1-947): 0: 806: 100.00
+	Hs
		91795 C9JN51_HUMAN (1-236): 2.74e-27: 110: 100.00		M3K14_HUMAN (1-947): 0: 806: 100.00
+	Mm
		312475 NEMO_MOUSE (1-407): 4.92e-55: 189: 87.22		AKT1_MOUSE (286-713): 4.73e-132: 407: 20.22
+	Hs
		728506 NEMO_HUMAN (1-407): 4.37e-54: 186: 100.00		AKT1_HUMAN (286-713): 1.97e-131: 406: 20.22
+	Hs
		122988 NEMO_HUMAN (1-407): 4.37e-54: 186: 100.00		SGK1_HUMAN (354-729): 1.62e-116: 365: 21.19
+	Hs
		297104 ITSN1_HUMAN (21-391): 3.79e-35: 140: 14.21		PAK3_HUMAN (134-674): 2.32e-128: 400: 20.11
+	Hs
		920411 NEMO_HUMAN (1-407): 4.37e-54: 186: 100.00		PLK1_HUMAN (406-781): 7.6e-107: 345: 26.87
+	Hs
		1095434 OPTN_HUMAN (55-406): 3.37e-32: 130: 27.25		AAPK1_HUMAN (374-909): 4.26e-126: 394: 17.48
+	Hs
		930775 OPTN_HUMAN (55-406): 3.37e-32: 130: 27.25		AAPK2_HUMAN (386-927): 8.94e-126: 393: 15.76
+	Hs
		587568 DESP_HUMAN (33-375): 5.08e-20: 94.7: 15.03		AKT1_HUMAN (286-713): 1.97e-131: 406: 20.22
+	Hs
		919990 ITSN1_HUMAN (21-391): 3.79e-35: 140: 14.21		PLK1_HUMAN (406-781): 7.6e-107: 345: 26.87
+	Hs
		563007 MYH6_HUMAN (56-370): 1.96e-10: 65: 15.87		STK4_HUMAN (405-650): 2.19e-99: 321: 30.80
+	Hs
		563052 MYH8_HUMAN (10-377): 3.1e-10: 64.3: 12.16		STK4_HUMAN (405-650): 2.19e-99: 321: 30.80
+	Mm
		107132 NEMO_MOUSE (1-407): 4.92e-55: 189: 87.22		F8VQ72_MOUSE (370-643): 4.85e-24: 111: 30.52
+	Hs
		1490933 NEMO_HUMAN (1-407): 4.37e-54: 186: 100.00		M3K2_HUMAN (386-626): 1.28e-24: 112: 33.60
+	Hs
		1407271 NEMO_HUMAN (1-407): 4.37e-54: 186: 100.00		M3K3_HUMAN (373-612): 7.4e-23: 106: 32.14
+	Hs
		587584 DESP_HUMAN (33-375): 5.08e-20: 94.7: 15.03		M3K8_HUMAN (379-647): 2.69e-29: 124: 30.66
+	Hs
		587851 DESP_HUMAN (33-375): 5.08e-20: 94.7: 15.03		STK24_HUMAN (405-647): 5.62e-20: 95.9: 33.33
+	Hs
		563009 MYH6_HUMAN (56-370): 1.96e-10: 65: 15.87		STK3_HUMAN (405-647): 1.3e-20: 98.2: 31.73
+	Hs
		563053 MYH8_HUMAN (10-377): 3.1e-10: 64.3: 12.16		STK3_HUMAN (405-647): 1.3e-20: 98.2: 31.73